Research comparison
Thymosin Alpha-1 vs TB-500
Side-by-side comparison of research status, mechanisms, pharmacokinetics, and administration routes.
Thymosin Alpha-1 is a naturally occurring 28-amino-acid peptide derived from thymosin fraction 5 of the thymus gland. Approved in over 35 countries for hepatitis B, hepatitis C, and as an immune adjuvant in cancer therapy, it enhances T-cell maturation, dendritic cell function, and NK cell activity. Research continues to expand into sepsis, COVID-19, autoimmune conditions, and vaccine response enhancement.
Research Status
FDA Approved
Half-Life
~2 hours
Molecular Formula
C₁₂₉H₂₁₅N₃₃O₅₅
Molecular Weight
3108.29 Da
CAS Number
62304-98-7
Research Categories
Immune Support, Anti-Aging & Longevity
Routes of Administration
TB-500 is a synthetic version of the active region of Thymosin Beta-4, a naturally occurring peptide found in virtually all human cells. Research shows it promotes actin polymerization and cell migration, which accelerates wound healing, muscle repair, and vascular growth. It is particularly studied for its ability to reduce inflammation and promote cardiac tissue repair.
Research Status
Preclinical Research
Half-Life
~6–8 hours
Molecular Formula
C₂₁₂H₃₅₀N₅₆O₇₈S
Molecular Weight
4963.44 Da
CAS Number
77591-33-4
Research Categories
Healing & Recovery, Muscle & Performance, Cardiovascular
Routes of Administration
Full mechanism comparison
Mechanism of action, pharmacokinetics, and research findings comparison available on the Researcher plan.
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