Peptide Database

Cathelicidin · hCAP18/LL-37

LL-37 is the only known human cathelicidin antimicrobial peptide, derived from the C-terminus of hCAP18 protein. It exhibits broad-spectrum antimicrobial activity against bacteria, fungi, and viruses by disrupting microbial membranes. Beyond direct killing, LL-37 modulates inflammation, promotes wound healing, and may have anticancer properties. Research focuses on chronic wound care, infection, and skin disorders like rosacea.

Tβ4 · LKKTETQ

Thymosin Beta-4 is the full-length 43-amino-acid peptide and one of the most abundant intracellular proteins in mammalian cells. It sequesters G-actin, regulating actin polymerization and cell motility, which underpins its role in wound healing, cardiac repair, and immune cell migration. Clinical trials have examined it for dry eye disease, epidermolysis bullosa, and cardiac repair after myocardial infarction.