Peptide Database

Long R3 IGF-1 · Insulin-like Growth Factor 1 Long R3

IGF-1 LR3 is a modified version of Insulin-like Growth Factor-1 with an arginine substitution and 13-amino-acid N-terminal extension, which reduces binding to IGF-binding proteins and extends its half-life. It promotes muscle cell hyperplasia and hypertrophy by activating the PI3K/AKT/mTOR pathway. Research explores its role in muscle wasting, recovery from injury, and anabolic signaling.

PEGylated Mechano Growth Factor

PEG-MGF is a PEGylated (polyethylene glycol-modified) form of Mechano Growth Factor, designed to dramatically extend its biological half-life from minutes to days while preserving activity. PEGylation allows systemic delivery and sustained satellite cell activation without the need for local injection. Research shows enhanced muscle hypertrophy signaling compared to unmodified MGF.