Peptide Database

Hydrolyzed Collagen · Collagen Hydrolysate

Hydrolyzed collagen peptides are short-chain amino acid sequences (2–20 amino acids) produced by enzymatic hydrolysis of collagen. Research demonstrates that specific collagen dipeptides and tripeptides (Pro-Hyp, Hyp-Gly) are absorbed intact, reach fibroblasts in skin and joints, and stimulate collagen and hyaluronic acid synthesis. Meta-analyses support effects on skin elasticity, wrinkle depth, joint pain, and muscle mass when combined with resistance exercise.

Copper Peptide GHK · Glycyl-L-histidyl-L-lysine copper

GHK-Cu is a naturally occurring copper-binding tripeptide found in human plasma, saliva, and urine. Research demonstrates it stimulates collagen, elastin, and glycosaminoglycan synthesis, promotes wound healing, reduces inflammation, and activates protective antioxidant genes. Plasma levels decline with age, making it a significant anti-aging research target.

C₁₄H₂₄CuN₆O₄ · 340.84 Da (free ligand)

Matrixyl · Pal-KTTKS

Palmitoyl Pentapeptide-4 (Matrixyl) is a lipopeptide widely used in cosmetic anti-aging formulations. It is derived from the procollagen type I sequence and acts as a matrikine, signaling skin cells to produce collagen, elastin, fibronectin, and hyaluronic acid. Clinical studies demonstrate measurable reduction in wrinkle depth and improved skin elasticity with topical application.

Pal-GHK · Matrixyl component

Palmitoyl Tripeptide-1 is a lipopeptide created by palmitoylating GHK (glycyl-histidyl-lysine), the same sequence as GHK-Cu without copper. The palmitoyl group enhances skin penetration, while the GHK sequence signals fibroblasts to upregulate collagen, elastin, and hyaluronic acid synthesis. It is a primary active ingredient in Matrixyl formulations and widely used in anti-aging cosmetics with clinical data supporting wrinkle reduction.

Arg-Gly-Asp · Integrin-binding peptide

RGD (Arg-Gly-Asp) is a tripeptide sequence found in many extracellular matrix proteins (fibronectin, vitronectin, collagen) that serves as the primary recognition motif for integrin receptors. RGD-containing peptides and scaffolds are extensively used in biomaterials research to promote cell adhesion, migration, and proliferation for tissue engineering, wound healing, and regenerative medicine applications.

Lys-Glu · KE dipeptide

Vilon is a synthetic dipeptide (Lys-Glu) developed at the St. Petersburg Institute of Bioregulation and Gerontology as a vascular cytoprotective peptide. Research demonstrates it reduces vascular endothelial cell aging, suppresses excessive collagen synthesis, and modulates the renin-angiotensin system. Long-term animal studies show improved vascular function and survival; it is often studied as part of peptide longevity protocols.