Peptide Database

Acetyl Octapeptide-3

SNAP-8 is an extended version of Argireline (an octapeptide vs hexapeptide), designed with enhanced SNARE-inhibiting potency. By more completely blocking the formation of the SNARE complex, it more effectively reduces muscle contraction at treated sites. Cosmetic research shows superior wrinkle reduction efficacy compared to Argireline at equivalent concentrations, particularly in forehead lines.

SP · NK1 ligand

Substance P is an 11-amino-acid neuropeptide of the tachykinin family and a primary neurotransmitter of pain signaling in the spinal cord. It binds NK1 receptors to mediate neurogenic inflammation, pain hypersensitivity, and emotional processing. NK1 antagonists have been developed for pain, depression (aprepitant), and nausea. Research also implicates substance P in wound healing, immune activation, and neuroinflammation.

Dipeptide Diaminobutyroyl Benzylamide Diacetate

Syn-Ake is a synthetic dipeptide that mimics the mechanism of waglerin-1, a peptide found in Temple Viper venom, by antagonizing muscular nicotinic acetylcholine receptors and reducing muscle contraction. Applied topically, it reduces the depth of expression lines by temporarily relaxing facial muscles. It has become a common high-end cosmetic ingredient positioned as a non-injectable alternative to botulinum toxin.

Thymosin Beta-4 Fragment · Tβ4 fragment

TB-500 is a synthetic version of the active region of Thymosin Beta-4, a naturally occurring peptide found in virtually all human cells. Research shows it promotes actin polymerization and cell migration, which accelerates wound healing, muscle repair, and vascular growth. It is particularly studied for its ability to reduce inflammation and promote cardiac tissue repair.

C₂₁₂H₃₅₀N₅₆O₇₈S · 4963.44 Da

Serum Thymic Factor · Facteur Thymique Sérique

Thymulin is a nonapeptide produced exclusively by thymic epithelial cells, requiring zinc for biological activity. It promotes T-cell differentiation, enhances cytokine production, and is a key marker of thymic function. Circulating thymulin levels decline with age, paralleling thymic involution. Research examines its role in autoimmunity, inflammatory diseases, and as a zinc-dependent immune regulator in aging.

Lys-Glu · KE dipeptide

Vilon is a synthetic dipeptide (Lys-Glu) developed at the St. Petersburg Institute of Bioregulation and Gerontology as a vascular cytoprotective peptide. Research demonstrates it reduces vascular endothelial cell aging, suppresses excessive collagen synthesis, and modulates the renin-angiotensin system. Long-term animal studies show improved vascular function and survival; it is often studied as part of peptide longevity protocols.

Alpha-Melanocyte-Stimulating Hormone · α-Melanotropin

α-MSH is an endogenous 13-amino-acid peptide derived from POMC (pro-opiomelanocortin). It activates MC1R to stimulate melanin production in skin, MC4R to suppress appetite and regulate energy expenditure, and MC3R/MC1R to exert potent anti-inflammatory effects. It is the parent compound from which many synthetic melanocortin analogs (Melanotan I, II, PT-141, KPV) were derived and remains a cornerstone of melanocortin pharmacology research.