Peptide Database

Thymosin Beta-4 Fragment · Tβ4 fragment

TB-500 is a synthetic version of the active region of Thymosin Beta-4, a naturally occurring peptide found in virtually all human cells. Research shows it promotes actin polymerization and cell migration, which accelerates wound healing, muscle repair, and vascular growth. It is particularly studied for its ability to reduce inflammation and promote cardiac tissue repair.

C₂₁₂H₃₅₀N₅₆O₇₈S · 4963.44 Da

Tβ4 · LKKTETQ

Thymosin Beta-4 is the full-length 43-amino-acid peptide and one of the most abundant intracellular proteins in mammalian cells. It sequesters G-actin, regulating actin polymerization and cell motility, which underpins its role in wound healing, cardiac repair, and immune cell migration. Clinical trials have examined it for dry eye disease, epidermolysis bullosa, and cardiac repair after myocardial infarction.